PUBLICATIONS

PubMed:

Prof. Dr. med. Leif Erik Sander

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Selected Publications:

  1. Kreye J*, Reincke SM*, Kornau HC, Sanchez-Sendin E, Corman VM, Liu H, Yuan M, Wu NC, Zhu X, Lee CD, Trimpert J, Hoeltje M, Dietert K, Stoeffler L, von Wardenburg N, van Hoof S, Homeyer MA, Hoffmann J, Abdelgawad A, Gruber AD, Bertzbach LD, Vladimirova D, Li LY, Barthel PC, Skriner K, Hocke AC, Hippenstiel S, Witzenrath M, Suttorp N, Kurth F, Franke C, Endres M, Schmitz D, Jeworowski LM, Richter A, Schmidt ML, Schwarz T, Mueller MA, Drosten C, Wendisch D, Sander LE, Osterrieder N, Wilson IA, Pruess H. A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model. Cell 2020, Sep 23  https://doi.org/10.1016/j.cell.2020.09.049
  2. Schulte-Schrepping J*, Reusch N*, Paclik D*, Baßler K*, Schlickeiser S*, Zhang B*, Krämer B*, Krammer T*, Brumhard S*, Bonaguro L*, De Domenico E*, Wendisch D*, (…), Schultze JL*#, Aschenbrenner AC*#, Li Y*#, Nattermann J*#, Sawitzki B*#, Saliba AE*#, Sander LE*#. Severe COVID-19 is marked by a dysregulated myeloid cell compartment. Cell. 2020 Aug 5. https://doi.org/10.1016/j.cell.2020.08.001
  3. Braun J*, Loyal L*, Frentsch M*, Wendisch D, Georg P, Kurth F, Hippenstiel S, Dingeldey M, Kruse B, Fauchere F, Baysal E, Mangold M, Henze L, Lauster R, Mall MA, Beyer K, Röhmel J, Voigt S, Schmitz J, Miltenyi S, Demuth I, Müller MA, Hocke A, Witzenrath M, Suttorp N, Kern F, Reimer U, Wenschuh H, Drosten C, Corman VM, Giesecke-Thiel C*, Sander LE*, Thiel A*. SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19. Nature. 2020 Jul 29. doi: 10.1038/s41586-020-2598-9
  4. Chua RL*, Lukassen S*, Trump S*, Hennig BP*, Wendisch D*, Pott F, Debnath O, Thürmann L, Kurth F, Völker MT, Kazmierski J, Timmermann B, Twardziok S, Schneider S, Machleidt F, Müller-Redetzky H, Maier M, Krannich A, Schmidt S, Balzer F, Liebig J, Loske J, Suttorp N, Eils J, Ishaque N, Liebert UG, von Kalle C, Hocke A, Witzenrath M, Goffinet C, Drosten C, Laudi S, Lehmann I*, Conrad C*, Sander LE*, Eils R*. COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. Nat Biotechnol 2020 Jun 26. doi: 10.1038/s41587-020-0602-4
  5. Herold S and Sander LE. Towards a universal flu vaccine. Science 2020;367:852-853
  6. Georg P and Sander LE. Innate sensors that regulate vaccine responses. Curr Opin Immunol 2019;59:31-41
  7. Ugolini M*, Gerhard J*, Burkert S*, Jensen KJ, Georg P, Ebner F, Volkers S, Thada S, Dietert K, Bauer L, Schäfer A, Helbig ET, Opitz B, Kurth F, Sur S, Dittrich N, Gaddam S, Blander JM, Benn CS, Blohm U, Gruber AD, Hutloff A, Hartmann S, Boekschoten MV, Müller M, Jungersen G, Schumann RR, Suttorp N, Sander LE. Recognition of microbial viability via TLR8 promotes T follicular helper cell differentiation and vaccine responses. Nat Immunol  2018   free full-text
  8. Garaude J, Acín-Pérez R, Martínez-Cano S, Enamorado M, Ugolini M, Nistal-Villán E, Hervás-Stubbs S, Pelegrín P, Sander LE, Enríquez JA, Sancho D. Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense. Nat Immunol 2016;17(9):1037-45.
  9. Blander JM, Sander LE. Beyond pattern recognition: five immune checkpoints for scaling the microbial threat. Nat Rev Immunol  2012 12:215-25.
  10. Sander LE, Davis MJ, Boekschoten MV, Amsen D, Dascher CC, Ryffel B, Swanson JA, Müller M, Blander JM. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature 2011 474:385-9