PUBLICATIONS

PubMed:

Prof. Dr. med. Stefan Hippenstiel

Dr. med. Bettina Temmesfeld-Wollbrück

Dr. vet. med. Janine Zahlten

For reprint requests please contact us.

Selected Publications:

  1. Peter A, Fatykhova D, Kershaw O, Gruber AD, Rueckert J, Neudecker J, Toennies M, Bauer TT, Schneider P, Schimek M, Eggeling S, Suttorp N, Hocke AC, Hippenstiel S. Localization and pneumococcal alteration of junction proteins in the human
    alveolar-capillary compartment. Histochem Cell Biol. 2017 Jun;147(6):707-719. doi: 10.1007/s00418-017-1551-y. Epub 2017 Mar 1. PubMed PMID: 28247028.
  2. Hocke AC, Suttorp N, Hippenstiel S. Human lung ex vivo infection models. Cell Tissue Res. 2017 Mar;367(3):511-524. doi: 10.1007/s00441-016-2546-z. Epub 2016 Dec 20. Review. PubMed PMID: 27999962.
  3. Griss K, Bertrams W, Sittka-Stark A, Seidel K, Stielow C, Hippenstiel S, Suttorp N, Eberhardt M, Wilhelm J, Vera J, Schmeck B. MicroRNAs Constitute a Negative Feedback Loop in Streptococcus pneumoniae-Induced Macrophage Activation.
    J Infect Dis. 2016 Jul 15;214(2):288-99. doi: 10.1093/infdis/jiw109. Epub 2016 Mar 16. PubMed PMID: 26984146.
  4. Fatykhova D, Rabes A, Machnik C, Guruprasad K, Pache F, Berg J, Toennies M, Bauer TT, Schneider P, Schimek M, Eggeling S, Mitchell TJ, Mitchell AM, Hilker R, Hain T, Suttorp N, Hippenstiel S, Hocke AC, Opitz B. Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue. PLoS One. 2015 Aug 28;10(8):e0137108. doi: 10.1371/journal.pone.0137108. eCollection 2015. PubMed
    PMID: 26317436; PubMed Central PMCID: PMC4552725.
  5. Zahlten J, Herta T, Kabus C, Steinfeldt M, Kershaw O, García P, Hocke AC, Gruber AD, Hübner RH, Steinicke R, Doehn JM, Suttorp N, Hippenstiel S. Role of Pneumococcal Autolysin for KLF4 Expression and Chemokine Secretion in Lung Epithelium. Am J Respir Cell Mol Biol. 2015 Oct;53(4):544-54. doi: 10.1165/rcmb.2014-0024OC. PubMed PMID: 25756955.
  6. Zahlten J, Kim YJ, Doehn JM, Pribyl T, Hocke AC, García P, Hammerschmidt S, Suttorp N, Hippenstiel S, Hübner RH. Streptococcus pneumoniae-Induced Oxidative Stress in Lung Epithelial Cells Depends on Pneumococcal Autolysis and Is Reversible by Resveratrol. J Infect Dis. 2015 Jun 1;211(11):1822-30. doi: 10.1093/infdis/jiu806. Epub 2014 Dec 15. PubMed PMID: 25512625.
  7. Knepper J, Schierhorn KL, Becher A, Budt M, Tönnies M, Bauer TT, Schneider P, Neudecker J, Rückert JC, Gruber AD, Suttorp N, Schweiger B, Hippenstiel S, Hocke  AC, Wolff T. The novel human influenza A(H7N9) virus is naturally adapted to efficient growth in human lung tissue. MBio. 2013 Oct 8;4(5):e00601-13. doi:
    10.1128/mBio.00601-13. Erratum in: MBio. 2014;5(4):doi:10.1128/mBio.01555-14.
    PubMed PMID: 24105764; PubMed Central PMCID: PMC3791893.
  8. Hocke AC, Becher A, Knepper J, Peter A, Holland G, Tönnies M, Bauer TT, Schneider P, Neudecker J, Muth D, Wendtner CM, Rückert JC, Drosten C, Gruber AD,  Laue M, Suttorp N, Hippenstiel S, Wolff T. Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs. Am J Respir Crit Care Med. 2013 Oct 1;188(7):882-6. doi: 10.1164/rccm.201305-0954LE. PubMed PMID: 24083868.
  9. Doehn JM, Fischer K, Reppe K, Gutbier B, Tschernig T, Hocke AC, Fischetti VA, Löffler J, Suttorp N, Hippenstiel S, Witzenrath M. Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia. J Antimicrob  Chemother. 2013 Sep;68(9):2111-7. doi: 10.1093/jac/dkt131. Epub 2013 Apr 30.
    PubMed PMID: 23633685.
  10. Zahlten J, Steinicke R, Bertrams W, Hocke AC, Scharf S, Schmeck B, Witzenrath M, Hammerschmidt S, Suttorp N, Hippenstiel S. TLR9- and Src-dependent expression  of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia. Eur
    Respir J. 2013 Feb;41(2):384-91. doi: 10.1183/09031936.00196311. Epub 2012 May
    31. PubMed PMID: 22653776.